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Advice On Home Mortgages Straight From The Financial Pros

Have you had a mortgage before? If you have, you surely realize the stress that a lack of knowledge can cause. Mortgage loans change often, and it is important to stay updated. Continue reading this article about home loans to get more info.

Try getting a pre-approved loan to see what your mortgage payments will be monthly. Shop around to see how much you are eligible for so you can determine your price range. Your lender can help you calculate estimated monthly payments.

Don't borrow the maximum amount you qualify for. You are the decider. The bank may be willing to give you more than you can comfortably afford. You want to enjoy your home. Consider your life, how your money is spent, and what you can afford and stay comfortable.

Before you actually fill out a mortgage application, you should have all the required documents well in order. Most lenders will require basic financial documents. They will likely include anything you typically submit to the IRS, and several pay stubs. Being organized will help the process move along Real Estate Cactus foreclosure listings smoother.

If you're thinking of getting a mortgage you need to know that you have great credit. Lenders carefully scrutinize credit histories to ascertain good risks. Do what you need to to repair your credit to make sure your application is approved.

Do not give up if you had your application denied. Instead, check out other lenders and fill out their mortgage applications. Different lenders have their own standards for giving loan approvals. This is why it will benefit you to apply with more than one lender.

If your mortgage has a 30 year term, you should think about paying an extra payment each month. The additional payment goes toward your principal. If you regularly make extra payments, the interest you pay will be significantly reduced and the loan will be paid off faster.

Just because you are denied once doesn't mean you should lose hope. Even though a lender has denied your application, there are lenders out there that will approve you. Keep looking at your options and shopping around. You might find a co-signer can help you get the mortgage that you need.

Pay close watch to the interest rates. Interest rates determine the amount you spend. Understanding interest rates will help you understand the total financing costs. You might end up spending more than you can afford if you are not careful with interest rates.

Look for help if you are finding it hard to pay your home mortgage. Think about getting financial counseling if you are having problems making payments. HUD-approved counselors exist in most regions. Such counselors can provide no-charge foreclosure prevention help. Go online to the HUD website or give them a call to locate an office near you.

Adjustable rate mortgages, or ARM, don't expire when the term is over. Instead, the rate is adjusted to match current bank rates. Therefore, it is possible that the interest rate will be very high.

Once you have taken out your mortgage, consider paying extra every month to go towards the principle. That will help you pay your loan off much more quickly. Paying as little as an additional hundred dollars a month could reduce the term of a mortgage by ten years.

It's imperative you understand how to go about getting the best possible mortgage. You want to find a home you can afford at the best rate possible for your situation. You don't want a home you can't afford. It is better to get a mortgage that fits your budget, so look for a company that will work with you.
16 Mayo 2016

Real Estate Selling With A Few Solid Tips

It's very important that you know and understand what you're doing when it comes to real estate. There is so much information available. However, it can be quite time consuming to go through all of the material. The following article will provide you with some very practical advice to see you through your real estate dealings successfully.

When you're selling your home, you should always set a price that is reasonable. Find out what comparable homes have sold for in the area and price your home at the median price. Don't set too high of a price; you'll only end up lowering it because nobody is willing to pay that price for your home.

Minor kitchen updates can do much to increase your home's attractiveness and value. Consider switching out just one appliance to become a focus piece and update the look. Other common kitchen upgrades include: installing a large wood block island in the center of the room, and adding hanging storage. It's quite expensive to install new kitchen cabinets, but you can update them with a lick of paint.

In certain areas homes sales are higher during more favorable seasons. Using fall decorations can help create a welcoming environment to potential buyers. Clear fallen leaves from the yard so that late season buyers aren't turned off my a messy garden.



Windows are always a strong selling point of any home, and having clean windows gives the property an updated look and feel. Clean windows will improve the lighting of your home, and make it look newer. The benefits will be obvious if you take the time to invest in vigorously cleaning your windows.

Clutter should be cleared from your property to make it more attractive to potential buyers. The closets should not only contain a limited number of items, but they should be clean and organized. Organize your kitchen cabinets and clean out as much stuff as you can. Be sure to leave gourmet foods that might serve to impress the potential buyer with how sophisticated the owners really are!

Open up all of your curtains when you show your home. One of the most attractive qualities of a home is the appearance and atmosphere caused by gorgeous natural lighting. Make sure your curtains, drapes, and blinds are as open as possible to let in as much light as you can. Open the windows to let some fresh air in: your buyers will notice a house that smells fresh.

Prepare your home for the market before the spring months arrive. Most new homeowners prefer to get moved in before the middle of summer.

Painting the inside of your home is a great way to prepare it for sale. It is a fairly inexpensive home improvement project that you can most likely complete yourself. A fresh coat of paint can make walls look new again. Just be sure that the color you choose is a neutral one, something like off-white.

Unless your floors are in bad shape, don't waste your money replacing them. Installing new flooring is a major expense, and the long-term benefits will accrue to whoever is living there, not to you. Instead, clean the floor thoroughly and temporarily fix any bad spots to prevent potentially buyers from being turned off your property by the flooring.

While it is important to make sure the interior of your home is in good shape when you are selling it, don't ignore the landscaping. If a buyer sees a lawn a foot tall and full of weeds, they will most likely assume that the house is in a similar condition and will not even enter.

Make a realistic assessment of potential risks before you set out to invest in real estate. There are downsides that come with being new at real estate investment ventures, and new investors will learn those things the hard way. Learn more about the business of investing in real estate before you begin spending your money.

Many people choose whatever real estate agent values their property at the highest price, while others select the agent that's valued the property and the lowest price, but it's best to work with someone who's in the middle. If the agent quotes your home as being a high value, he may be just trying to win you over as a Real Estate Cactus foreclosure listings client and may not be realistic. If the agent undervalues your home, it could end up costing you a lot of money.

Hopefully this article has been helpful to you. All you need to do now is apply what you've learned to your circumstances. Time invested in learning about the real estate arena will greatly improve your profit when you sell.

14 Mayo 2016
Admin · 21 vistas · Escribir un comentario

Stressed About Your Wedding? Get Some Relief Right Here

When the wedding plans start causing you stress, remember that the day is about your love for your fiance. Here's some tips to help make your wedding wonderful.

Are you bringing in food yourself to your reception? Visit a wholesale store to stock up. If you shop at a wholesale store, you will get much more for your dollar than the regular supermarket. Think about asking friends to help you out with food costs.

The pictures you will have taken on your wedding day are meant to be a memento of your happy day for a lifetime. It pays to spend the extra cash to hire a wedding photographer in order to reduce the chance of some amateur screwing up your wedding photos.

Pick a reasonable dress that you won't have to starve to get into. All you are going to do is tire very easily and not have the energy to enjoy the big day you have been torturing yourself to plan. You definitely don't want to end up fainting on your big day. If weight is a concern or you are having a tough time with the dress, simply have it let out a hair to accentuate your body more comfortably.

Think about wedding transportation. For people who need a ride back to their hotels at night, arrange to have taxis and limos ready for them. This is especially good thinking because many guests at your wedding are likely to be drinking.

Brides with sensitive skin can de-stress before a trip down the aisle by adopting a skincare routine that creates a glowing, revitalized appearance that won't cause breakouts, hives, or irritation. Brides can use facial treatments with ingredients that include oatmeal, sea salt and rose, They keep skin bright and leaves it smooth.

Don't overcrowd your wedding reception tables with excessive flowers. Often, flowers interfere with guests being able to converse across the table. Also, some of your guests may have allergies to the flowers. Adorn the tables with romantic, non-scented candles instead.

Full length mirrors are great for practicing the "aisle-walk." If you will be wearing heels, this is even more crucial. If you're scared of turning your ankle, go with attractive flats instead. Reducing the risk of falling is better than going with the best-looking footwear.

Sweet cupcakes are great alternatives to an expensive cake. These treats are not only affordable and convenient, but you can do many things with them. Those who were invited will grab them at will and consume them rather quickly as opposed to wrapping the pieces they grab in a napkin and forgetting it.

It can be a friend or a family member, they just need to help you carry your gear wherever you go. A family member or a close friend will be able to gather families together for group photographs.

When you choose to invite family members to join you at your destination wedding, ask them if they would like to stay for the honeymoon, as well! It's a great way to get a group discount and they can share in the special memories you are going to make at your chosen destination. This will give your family something really special to remember too!

Your guests shouldn't be kept waiting during your lengthy photo sessions. Pictures of the bride, groom, bridesmaids and groomsmen can be snapped in advance. Even pictures with parents can be shot in advance, reducing the time that guests must wait for you to arrive at your reception.

Offer sweet treats between courses to keep your guests amused. Opt for sugar roses that match your wedding color palette, edible, sugared petals, or thin, flavorful crackers to whet the appetite.

Be considerate of your guests and their travel arrangements when planning a destination wedding. Some guests may have conflicts with the timing or with the costs of attending. Ample time should be approximately eight months in advance, providing them with "save the date" invitations.

Find a wedding day photographer who is able to capture memories. Therefore, it is essential you ask the right questions when interviewing photographers. Ask how they will capture those precious moments. You should be comfortable with the photographer's style and presence at your wedding.

Always do your research before you hire a band or DJ. Try to get good references from people familiar with their work. When drawing up a contract, make sure that the date, the hours you expect to have them working, the pay and any other variables are all accounted for. This is important, as you want the music for your wedding to be perfect.

Plan ahead for your wedding, so that you can relax about it and enjoy the planning process. Above all, remember why you're doing this, and that getting married is a happy and exciting milestone in your life. The wedding is the first step toward your life together, so be prepared and it should go smoothly!
10 Mayo 2016
Admin · 1244 vistas · Escribir un comentario

Selecting Entities on Sites and Performing Tasks On Them Through Google

Visitors to a website may want to perform certain actions related to Entities (specific places or people or things) that are displayed to them on the Web.

For example, at a page for a restaurant (an entity), a person viewing the site may want to create a reservation or get driving directions to the restaurant from their current location. Doing those things may require a person to take a number of steps, such as selecting the name of the restaurant and copying it, pasting that information into a search box, and submitting it as a search query, selecting the site from search results, determining if making a reservation is possible on the site, and then providing information necessary to make a reservation; getting driving directions may also require multiple steps.

Using a touch screen device may potentially be even more difficult because the site would possibly then be limited to touch input.

A patent granted to Google this week describes a way to easily identify an entity such as a restaurant on a touch device, and select it online and take some action associated with that entity based upon the context of a site the entity is found upon. Actions such as booking a reservation at a restaurant found on a website, or procuring driving directions to that site, or other actions could be easily selected by the user of a site.

The patent is:

Semantic selection and purpose facilitation

Inventors: Paul Nordstrom, Casey Stuart Whitelaw,

Assignee: Google

US Patent 9,305,108

Granted April 5, 2016

Filed: October 5, 2012

Abstract

Computer-implemented methods for proposing actions to a user to select based on the users predicted purpose for selecting content are provided. In one aspect, a method includes receiving an identifier of a referent entity associated with user-selectable content, identifying, based on a prediction of a purpose in selecting the content, at least one action to be executed that is associated with the entity, and providing, for display, at least one identifier of the at least one action to the device for selection by a user. Systems, graphical user interfaces, and machine-readable media are also provided.

How an entity and actions might be selected by a site visitor

A person searches for a site using text such as sushi restaurants in Mountain View. That person then circles the text we love Ramen Sushi out of all of the places weve been to on the web page they found with that search, by circling the text using a touch input. Based on the content they chose and the context of their selection of that text, The system decides that viewer of the page has selected Ramen Sushi, and it proposes that entity to the user. The user can confirm that, and is then given a number of actions to perform on the entity based on a context of that selection.

Someone circles an entity on a touch screen to perform actions on it.Someone circles an entity on a touch screen to perform actions on it.

The context can include:

The current location of the deviceA past location of the deviceThe type of the device A previous action associated with the entity taken by the user or another userA search queryInformation on another user associated with the userThe file from which the user-selectable content was selectedThe remaining content from which the user-selectable content was selected

Actions might then be displayed that could include:

Directions to Ramen SushiMake a reservation at Ramen SushiOperating hours for Ramen Sushi Reviews of Ramen Sushi

Once an action is chosen, it can be performed by the system.

Entities are contained in an entity database, which may contain attributes or properties associated with the entity, and those can be pre-defined, and can have associated descriptors such as location, restaurant, and phone number. An entity that is a person such as George Washington can have an associated descriptor notable person.

The patent tells us that entities that are listed in the entity database can be associated with one or many user purposes and/or actions based on an associated descriptor.

A purpose is something that a user would want to do or find out with respect to an entity that selected. These actions are shown in a menu to the user as choices of actions to take regarding selected entities. These purposes may be referred to as a task. The patent provides a number of examples, that include:

play (e.g. for games and sports), rate or evaluate, travel to, contact, communicate, share, record, remember, dine, consume, experience or enjoy (e.g. art, music), reserve (tickets, etc.), compare, learn, study, understand, purchase, repair, fix, teach, cook, and make. For the example purpose dine, an example sub-purpose can be eat dinner, from which example sub-purposes can be make reservation, get directions, and find parking.

The patent tells us that users can select multiple entities of the same type at the same time to compare them.

Entities, purposes, and actions can be added to the entity database either manually or automatically with a user (or even an owner of the entity) adding information. The patent provides some examples of how information might be added to the entity database, but it seems to be fairly wide open under the patent.

The patent doesnt mention Schema vocabulary, which would be one way for a site owner to add entity information to an entity database.

Entities may be products, and actions presented to a user could include providing a review of the product, identifying a seller of the product, providing a price for the product, or providing an offer (e.g., discount or coupon) associated with the product. If the entity is a service, such as watching a movie or a plumber for hire, the actions that may be presented to the user could include providing a review of the service, identifying an availability of the service (e.g., show times), identifying a location where the service is being provided (e.g., an address of the plumber), or providing an option to purchase the service (e.g., purchasing tickets for the movie or rates offered by the plumber).

Take Aways

The entity database described in this patent could be a very big one, containing multiple businesses (like those from Google Maps), multiple products, multiple people (like those found at a knowledge base like Wikipedia), and multiple potential actions and tasks associated with those entities.

This seems to be a fairly aspirational patent, which might require a lot of steps being put into place before it is implemented. It does present a vision of how entities on the web could eventually be acted upon by people who see them in web pages.

This could be something that Google may intend to do, and some of the pieces for it are in place, such as a knowledge graph filled with entities, and a schema system that is extendable. Its interesting seeing a patent that lays out a framework like this one does. Is this a future path that Google will follow? We may need to wait to see.

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22 Avr 2016
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Google Assigns 148 Medical Patents to Verily Life Sciences

verily logo

Back in September of 2009, I wrote a blog post that I titled Googles 10 Oddest Patents. The first of those that I included in that list was one named Instrument for medical purposes, I included it mostly because Google was a search company, and it felt odd that Google would have a patent on a medical process. That one used ultrasonic sound to investigate the structural makeup of biological tissue in organs and vessels.

Times have changed, and since that time, Google has restructured and put itself under a holding company structure with the name Alphabet running all elements of the company. A branch of the Company had evolved that was being referred to as Google Life Sciences, and it changed names recently as well, to Verily Life Sciences.

What role and what kind of impact might these new subsidiary have? I was wondering if Google would make changes to the patent assignments it had made along with the name changes, and I was surprised to see them do so, where they assigned 148 patents to Verily Life Sciences on two different days. Its an interesting list, and Ive provided it here. They may technically have ownership under other patents as well, but this list points to a number that could possibly become products that the company offers to the public, after any government approval that they may need to pursue.

This recent story highlights the kind of approval that medical devices need to acquire before they are used for medical purposes: Google offshoot Verily reveals connectivity device to aggregate medical data.

Verily may become involved in medical studies, like this one described to be between Vanderbilt and Verily: Vanderbilt, Googles Verily to Launch Precision Medicine Initiative Cohort.

This article provides some possible valuations as to what kinds of money are potentially available to companies providing healthcare products and benefits to people: How Alphabet Is Eyeing The Lucrative Healthcare Industry With Verily.

This article presents healthcare as a potentially very lucrative field for Google to be entering: New Miniature Continuous Glucose Monitoring Devices from DexCom and Verily (Google Life Sciences) Promise to Make Glucose Monitoring Wearable and Affordable.

This followup to that story shows that plans are being made to release products over the next few years: Googles Verily, Dexcom aim to launch mini glucose monitor in 2018, with next-gen by 2021.

Ive written about one of these patents in the past, in the post Google Files Patent For Wearable Nanotechnology Anti-Cancer Technology, and that patent is included in the assignment, as is a patent for a Star Trek like Needle free blood draw device that was published this past December.

I decided to publish links to these patent filings, and information about the dates they were filed, and when they were either published (for the pending patent applications) or granted (for the many that have been granted so far). There are many contact lens focused patents in the group, but other ones that have different purposes as well. If any stand out to you as interesting in some way, please share with us, and let us know why.

There seem to be many opportunities available to Google to pursue, and Im excited that so many options are open to them. I also like that now that Im seeing patents that describe medical devices coming from Google, that enough has changed that I no longer think of them as odd, but am instead excited to see how those may be used. These are exciting times, and it appears that Google is off to a good start addressing medical problems.

Contact Lenses

Inventors: Brian Otis, Babak Amirparviz

Filed Jul 10, 2014

Granted Aug 5, 2014

Abstract:

Apparatus, systems and methods for facilitating iris-scanning contact lenses and/or biometric identification employing iris scanning contact lenses are provided. In one implementation, the contact lens can include: a transparent substrate formed to cover at least a portion of an iris of an eye; and a circuit. The circuit can include: one or more light sensors disposed on or within the transparent substrate and that detects light filtered through the iris and incident on the one or more light sensors; readout circuitry, operably coupled to the one or more light sensors, that outputs information indicative of the light filtered through the iris and incident on the one or more light sensors; and a power component that supplies power to the readout circuitry. In various implementations, the contact lens can be employed in systems and/or methods associated with authentication and identification.

Contact Lenses With Hybrid Power Sources

Inventors: Nathan Pletcher, Brian Otis

Filed Jul 26, 2012

Published Jul 10, 2014

Abstract:

Apparatus, systems and methods of contact lenses with power sources are provided. In some aspects, a contact lens can include a substrate; and a circuit. The circuit can include: one or more sensors disposed on or within the substrate; circuitry disposed on at least a portion of the substrate; one or more photovoltaic cells disposed on at least a portion of the substrate; and a hybrid power component that supplies at least one of two or more different types of power to the circuitry, wherein at least one of the two or more different types of power is radio frequency/inductive power. In various aspects, other types of power can be solar and/or microelectromechanical system power. Additionally, in various aspects, photovoltaic cells can be arrayed in different configurations and/or over a significant portion of a viewing surface of the contact lens. In some aspects, the photovoltaic cells can be transparent.

Contact Lens Employing Optical Signals for Power and/or Communication

Inventors: Nathan Pletcher, Brian Otis

Filed Jul 26, 2012

Granted Oct 13, 2015

Abstract:

Apparatus, systems and methods employing contact lens sensors are provided. In some aspects, a contact lens includes a substrate that forms at least a portion of the body of the contact lens; an optical communication device disposed on or within the substrate; and a photodetector disposed on or within the substrate, wherein the photodetector harvests light emitted from a device and generates power from the harvested light. In some aspects, an apparatus comprises a tag having a circuit including: an optical communication device; and a photodetector that harvests light received and generates power from the harvested light. The tag can be disposed on or within a contact lens in various aspects.

Actuatable Contact Lenses

Inventors: Harvey Ho

Filed Aug 2, 2012

Granted Dec 30, 2014

Abstract:

Apparatus, systems and methods for facilitating actuatable contact lenses are provided. In one aspect, the contact lens can include: a substrate comprised of a material that is actuatable to at least one of change a base curvature from a first curvature to a second curvature or change a thickness from a first thickness to a second thickness; and a control component, operably coupled to the material, that outputs actuation information to cause the material to actuate and at least one of change the base curvature of the material or change the thickness of the material. The contact lens can be actuated based on a condition associated with an environment surrounding the contact lens, a sensed prescription for an eye over which the contact lens is placed or based on a focal point of the eye. The material can include piezoelectric film, a shape memory alloy, hydrogel and/or silicone elastomer.

Contact Lenses Having Two-Electrode Electrochemical Sensors

Inventors: Zenghe Liu

Filed Aug 6, 2012

Published Jul 10, 2014

Abstract:

Apparatus, systems and methods employing contact lenses with two-electrode electrochemical sensors are provided. In some aspects, the contact lens includes: a substrate that forms at least part of a body of the contact lens; and a circuit, disposed on or within the substrate, and including a two-electrode electrochemical sensor. The two-electrode electrochemical sensor can include: a working electrode; and a combination reference-counter electrode. The electrochemical sensor can be an amperometric sensor that senses a biological feature of a wearer of the contact lens. The working electrode can generate a signal indicative of the sensed analyte, and the combination reference-counter electrode can pass the signal generated from the working electrode. The signal can be employed to determine the analyte concentration of a solution in contact with the contact lens.

Contact Lens with Integrated Pulse Oximeter

Inventors: Harvey Ho, Babak Amirparviz

Filed Aug 21, 2012

Granted Mar 3, 2015

Abstract:

Apparatus, systems and methods employing a contact lens having a pulse oximetry sensor to detect information indicative of a blood oxygen content and/or pulse rate of a wearer of the contact lens, are provided. In some aspects, a contact lens includes a substrate that forms at least part of a body of the contact lens and a pulse oximetry sensor located on or within the substrate that detects information associated with at least one of blood oxygen content or a pulse rate of a wearer of the contact lens. The pulse oximetry sensor comprises one or more light emitting diodes that illuminate a blood vessel of at least one of a region of an eye or an eyelid and a detector that receives light reflected from the blood vessel and generates the information.

Passive Surface Acostic Wave Communication

Inventors: Harvey Ho, Babak Amirparviz

Filed Sep 5, 2012

Granted Sep 2, 2014

Abstract:

This disclosure relates to systems and/or methods for detection of eye blinking by interrogating a passive surface acoustic wave based contact lens using an interrogation signal and interpreting reflections of the interrogation signal from the passive surface acoustic wave based contact lens.

In-Situ Tear Sample Collection and Testing Using a Contact Lens

Inventors: Zenghe Liu, James Etzkorn

Filed Sep 7, 2012

Published Jul 10, 2014

Abstract:

Apparatus, systems and methods employing contact lenses having one or more sensor that sense an analyte in tear fluid and one or more recesses that collect the tear fluid. In some aspects, a contact lens includes a substrate that forms at least part of a body of the contact lens and a recess formed within the substrate configured to collect tear fluid when the contact lens is worn. The contact lens further includes at least one sensor disposed within the substrate configured to sense presence of an analyte in the collected tear fluid.

Sensor

Inventors: Zenghe Liu, Babak Amirparviz

Filed Sep 17, 2012

Published Jul 24, 2014

Abstract:

Apparatus, systems and methods employing contact lenses having an electrochemical sensor to detect ethanol concentration of a wearer of the contact lens are provided. In some aspects, a contact lens includes a substrate that forms at least part of a body of the contact lens and an electrochemical sensor, disposed on or within the substrate, that detects information related to concentration of alcohol present in blood of a wearer of the contact lens.

Contact Lens that Facilitates Antenna Communication Via Sensor Impedance Modulation

Inventors: Brian Otis, Nathan Pletcher

Filed Sep 24, 2012

Granted Oct 28, 2014

Abstract:

Systems, contact lenses and methods that facilitate antenna communication via sensor impedance modulation are provided. In one aspect, a system can include a contact lens and a radio frequency (RF) reader. The contact lens can include a substrate; an RF antenna, disposed on or within the substrate; and a sensing component, disposed on or within the substrate, and directly coupled to the RF antenna, wherein the RF antenna is configured to change impedance value as a sensed value of the sensing component changes. The RF reader is external to the contact lens, and configured to interrogate the RF antenna with an RF signal. The RF reader can receive a reflected RF signal from the RF antenna in response to the interrogation. The magnitude, phase and/or a frequency of the reflected RF signal can be based on the impedance value of the RF antenna.

Contact Lens That Restricts Incoming Light To The Eye

Inventors: James Etzkorn, Brian Otis

Filed Sep 24, 2012

Granted Feb 24, 2015

Abstract:

This disclosure generally relates to systems and/or methods to restrict light entering an opening of an eye pupil by detecting pupil dilation, detecting incoming light intensity or direction, and adjusting light restricting properties of one or more light restricting regions of the contact lens based upon the detected pupil dilation parameters and incoming light intensity or direction.

Information Processing Method

Inventors: Ehsan Saeedi, Babak Amirparviz

Filed Sep 25, 2012

Published Mar 27, 2014

Abstract:

Systems, apparatus and methods including a contact lens that facilitates collection and/or processing of information associated with sensed features are provided. In one aspect, a system can include a contact lens and an analysis component external to the contact lens. The contact lens can include: a substrate; and a circuit, disposed on or within the substrate. The circuit can include: a plurality of sensors configured to sense respective features associated with a wearer of the contact lens; and a communication component configured to communicate information indicative of sensed features. The analysis component can be configured to: receive the information indicative of the sensed features; and generate statistical information based, at least, on the information indicative of the sensed features.

Facilitation of Temperature Compensation For Contact Lens Sensors and Temperature Sensing

Inventors: Zenghe Liu, Nathan Pletcher, Brian Otis

Filed Sep 25, 2012

Published Mar 17, 2015

Abstract:

Apparatus, systems and methods employing contact lens sensors are provided. In some aspects, a contact lens includes a substrate and a circuit. The circuit can include: one or more sensors disposed on or within the substrate, that sense a feature associated with a wearer of the contact lens; and a compensation circuit disposed on or within the substrate, coupled to the sensor(s) and that outputs information to adjust an output of the sensor(s). The compensation circuit can include: a temperature component that senses the temperature of the sensor(s); and a communication component that outputs information indicative of the temperature of the sensor(s), and receives information associated with adjusting the output of the sensor(s). In other aspects, a contact lens includes a circuit that senses the body temperature, or ambient temperature outside of the body, of the contact lens wearer. Sensor fusion and/or calibration can be performed based on the information.

Contact Lens Having a Chip Integrated Into a Polymer Substrate and Method of Manufacture

Inventors: James Etzkorn

Filed Sep 25, 2012

Published Mar 27, 2014

Abstract:

Contact lenses and methods of manufacture are provided. In one aspect, a method includes: positioning components in predefined locations on a first surface; applying pressure on the components employing a second surface; providing molten material between the first surface and the second surface and around the components; embedding the components in a substrate by cooling the molten material and causing the molten material to harden, the substrate being a substantially solid form of molten material; and removing the first surface and the second surface after embedding the components in the substrate. The method can also include: providing, on or within a contact lens, one of the components and the substrate into which the component is embedded. The first surface can include molds sized to receive and maintain the components at the predefined locations. The first surface and/or the second surface can be pre-treated with a non-stick coating such as Polytetrafluoroethylene.

Wearable Device

Inventors: Babak Amirparviz, Harvey Ho

Filed Sep 25, 2012

Granted Mar 24, 2015

Abstract:

Apparatus, systems and methods employing a contact lens that generates information indicative of a hydration level of an eye in which the lens is worn, are provided. In some aspects, a contact lens includes a substrate that forms at least part of a body of the contact lens and a hydration component that generates information associated with a hydration level of an eye in which the contact lens is worn.

Assembling Thin Silicon Chips on a Contact Lens

Inventors: James Etzkorn

Filed Sep 26, 2012

Granted Feb 24, 2015

Abstract:

A contact lens having a thin silicon chip integrated therein is provided along with methods for assembling the silicon chip within the contact lens. In an aspect, a method includes creating a plurality of lens contact pads on a lens substrate and creating a plurality of chip contact pads on a chip. The method further involves applying assembly bonding material to the each of the plurality of lens contact pads or chip contact pads, aligning the plurality of lens contact pads with the plurality of chip contact pads, bonding the chip to the lens substrate via the assembly bonding material using flip chip bonding, and forming a contact lens with the lens substrate.

Contact Lens Having an Uneven Embedded Substrate and Method of Manufacture

Inventors: James Etzkorn, Babak Amirparviz

Filed Sep 26, 2012

Granted Mar 24, 2015

Abstract:

Contact lenses and methods of manufacturing contact lenses are provided. In one aspect, a method includes: forming a substrate having an uneven surface; providing a sensor at a first region of the substrate; providing a chip at a second region of the substrate; and encapsulating the substrate, sensor and chip in a polymer. The method also includes: patterning interconnections from the first region of the substrate to the second region of the substrate; and patterning metal pads proximate to the second region of the substrate. The chip can be provided on a metal pad. The uneven surface can be a sloped surface or one or more sloped channels in the substrate, and the channels can be wide enough to receive interconnections for the chip and to receive the chip. Further, the substrate can be ring-shaped and curved prior to encapsulation.

In-Vitro Contact Lens Testing

Inventors: Zenghe Liu, James Etzkorn

Filed Sep 26, 2012

Granted Sep 2, 2014

Abstract:

Contact lens testing apparatuses and method for testing contact lenses for analytes are presented. In an aspect, a device is provided that includes a housing configured to hold one or more contact lenses, and a testing compartment provided within the housing and comprising a reagent, the reagent configured to facilitate a chemical reaction in response to the existence of a predetermined biomarker disposed on or within a contact lens placed in the testing compartment, wherein the chemical reaction produces a known result related to state information of an individual from which the biomarker was generated.

Facilitation of Tear Sample Collection and Testing Using a Contact Lens

Inventors: James Etzkorn, Zenghe Liu

Filed Sep 26, 2012

Published Mar 27, 2014

Abstract:

Apparatus, systems and methods employing contact lens sensors are provided. In some aspects, a contact lens includes a substrate and a circuit. The circuit can include: one or more sensors disposed on or within the substrate, that sense a feature associated with a wearer of the contact lens; and a compensation circuit disposed on or within the substrate, coupled to the sensor(s) and that outputs information to adjust an output of the sensor(s). The compensation circuit can include: a temperature component that senses the temperature of the sensor(s); and a communication component that outputs information indicative of the temperature of the sensor(s), and receives information associated with adjusting the output of the sensor(s). In other aspects, a contact lens includes a circuit that senses the body temperature, or ambient temperature outside of the body, of the contact lens wearer. Sensor fusion and/or calibration can be performed based on the information.

Image Capture Component on Active Lens

Inventors: Nathan Pletcher, Olivia Hatalsky, Babak Amirparviz

Filed Oct 8, 2012

Published Apr 10, 2014

Abstract:

This disclosure relates to systems and/or methods for capturing image data representing a scene in a gaze of a viewer via a thin image capture component integrated on or within a contact lens, processing the image data, and employing the processed image data to perform functions locally on the contact lens or remotely on one or more remote devices.

In-vitro Calibration Of An Ophthalmic Analyte Sensor

Inventors: Brian Otis, Zenghe Liu

Filed Oct 12, 2012

Published Apr 17, 2014

Abstract:

An eye-mountable device includes an electrochemical sensor embedded in a polymeric material configured for mounting to a surface of an eye. The electrochemical sensor includes a working electrode, a reference electrode, and a reagent that selectively reacts with an analyte to generate a sensor measurement related to a concentration of the analyte in a fluid to which the eye-mountable device is exposed. A calibration-solution measurement is obtained while the eye-mountable device is exposed to a calibration solution. A calibration value is determined based on at least the calibration-solution measurement and an analyte concentration of the calibration solution. A tear-film measurement is obtained while the eye-mountable device is mounted to an eye so as to be exposed to tear film. The analyte concentration of the tear film is determined based on at least the tear-film measurement and the calibration value.

Contact Lens and Method of Manufacture to Improve Sensor Sensitivity

Inventors: Jeffrey George Linhardt, James Etzkorn

Filed Oct 24, 2012

Granted Nov 3, 2015

Abstract:

Contact lenses and methods of manufacture are provided. A contact lens can include: an electronics substrate having components formed thereon and disposed within a contact lens forming (CLF) polymer, wherein a first one of the components is positioned at a first region of the electronics substrate and a second one of the components is positioned at a second region of the electronics substrate, the second region being opposite the first region; and a plurality of CLF polymer layers molded such that the plurality of CLF polymer layers has a first thickness in a region of the electronics substrate associated with the first one of the components and has a second thickness in a region of the electronics substrate associated with the second one of the components.

Encapsulated Electronics

Inventors: James Etzkorn, Babak Amirparviz

Filed Jan 15, 2013

Granted Oct 28, 2014

Abstract:

An eye-mountable device includes an electrochemical sensor embedded in a polymeric material configured for mounting to a surface of an eye. The electrochemical sensor includes a working electrode and a reference electrode that reacts with an analyte to generate a sensor measurement related to a concentration of the analyte in a fluid to which the eye-mountable device is exposed. An example assembly process includes: forming a sacrificial layer on a working substrate; forming a first layer of a bio-compatible material on the sacrificial layer; providing an electronics module on the first layer of the bio-compatible material, forming a second layer of the bio-compatible material to cover the electronics module; and annealing the first and second layers of the bio-compatible material together to form an encapsulated structure having the electronics module fully encapsulated by the bio-compatible material.

Method of Ring-Shaped Structure Placement in an Eye-Mountable Device

Inventors: Jeffrey George Linhardt, Harvey Ho

Filed Jan 17, 2013

Published Jul 17, 2014

Abstract:

An eye-mountable device includes an electrochemical sensor embedded in a polymeric material configured for mounting to a surface of an eye. The electrochemical sensor applies a stabilization voltage between a working electrode and a reference electrode to allow the amperometric current to stabilize before powering measurement electronics configured to measure the amperometric current and communicate the measured amperometric current. The electrochemical sensor consumes less power while applying the stabilization voltage than during the measurement. The measurement is initiated in response to receiving a measurement signal at an antenna in the eye-mountable device.

Standby Biasing Of Electrochemical Sensor To Reduce Sensor Stabilization Time During Measurement

Inventors: Nathan Pletcher, Brian Otis

Filed Jan 25, 2013

Published Jul 31, 2014

Abstract:

An eye-mountable device includes an electrochemical sensor embedded in a polymeric material configured for mounting to a surface of an eye. The electrochemical sensor applies a stabilization voltage between a working electrode and a reference electrode to allow the amperometric current to stabilize before powering measurement electronics configured to measure the amperometric current and communicate the measured amperometric current. The electrochemical sensor consumes less power while applying the stabilization voltage than during the measurement. The measurement is initiated in response to receiving a measurement signal at an antenna in the eye-mountable device.

Systems and Methods for Encapsulating Electronics in a Mountable Device

Inventors: James Etzkorn

Filed Mar 26, 2013

Granted Oct 20, 2015

Abstract:

A mountable device includes a bio-compatible structure embedded in a polymer that defines at least one mounting surface. The bio-compatible structure has a first side defined by a first layer of bio-compatible material, a second side defined by a second layer of bio-compatible material, an electronic component, and a conductive pattern that defines sensor electrodes. A portion of the second layer of bio-compatible material is removed by etching to create at least one opening in the second side in which the sensor electrodes are exposed. The etching further removes a portion of the first layer of bio-compatible material so as to create at least one opening in the first side that is connected to the at least opening in the second side. With this arrangement of openings, analytes can reach the sensor electrodes from either the first side or the second side of the bio-compatible structure.

Systems and Methods for Encapsulating Electronics in a Mountable Device

Inventors: James Etzkorn

Filed Mar 27, 2013

Granted Aug 25, 2015

Abstract:

A mountable device includes a bio-compatible structure embedded in a polymer that defines at least one mounting surface. The bio-compatible structure includes an electronic component having electrical contacts, sensor electrodes, and electrical interconnects between the sensor electrodes and the electrical contacts. The bio-compatible structure is fabricated such that it is fully encapsulated by a bio-compatible material, except for the sensor electrodes. In the fabrication, the electronic component is positioned on a first layer of bio-compatible material and a second layer of bio-compatible material is formed over the first layer of bio-compatible material and the electronic component. The electrical contacts are exposed by removing a portion of the second layer, a conductive pattern is formed to define the sensor electrodes and electrical interconnects, and a third layer of bio-compatible material is formed over the conductive pattern. The sensor electrodes are exposed by removing a portion of the third layer.

Utilizing Oscillator Frequency Divider Settings As A Temperature Sensor In Radio Frequency Applications

Inventors: Brian Patrick Otis, Nathan Pletcher, Daniel Yeager

Filed May 24, 2013

Granted May 5, 2015

Abstract:

Methods and systems for utilizing oscillator frequency divider settings as a temperature sensor are described herein. An example method may involve a reader device transmitting an RF signal to a tag device that includes an electronic oscillator configured to generate an oscillator signal with an oscillator frequency and a frequency adjuster configured to adjust the oscillator frequency with a frequency adjustment factor to provide a resulting frequency, the oscillator frequency being dependent on a temperature of the tag device and the resulting frequency being based on a reference frequency provided by the RF signal. The method may also involve the reader device receiving data from the tag device, the data being indicative of the oscillator frequency. The method may further involve the reader device determining an estimate of the temperature of the tag device based on at least the received data and a predetermined relationship between temperature and oscillator frequency.

Body-Mountable Devices and Methods for Embedding a Structure in a Body-Mountable Device

Inventors: James Etzkorn, Stephen ODriscoll

Filed Jun 14, 2013

Published Dec 18, 2014

Abstract:

Body-mountable devices and methods for embedding a structure in a body-mountable device are described. A body-mountable device includes a transparent polymer and a structure embedded in the transparent polymer. The transparent polymer defines a posterior side and an anterior side of the body-mountable device. The structure has an outer diameter and an inner diameter and includes a sensor configured to detect an analyte and an antenna. The antenna includes a plurality of conductive loops spaced apart from each other between the outer diameter and the inner diameter.

Physiological Measurement Using Wearable Device

Inventors: Andrew Conrad, Eric Peeters

Filed Jun 21, 2013

Published Dec 25, 2014

Abstract:

A wearable device includes a detector configured to detect a response signal transmitted from a portion of subsurface vasculature, the response signal being related to binding of a clinically-relevant analyte to functionalized particles present in a lumen of the subsurface vasculature. Program instructions stored in a computer readable medium of the device, and executable by a processor, may cause the device to determine a concentration of the clinically-relevant analyte based on the response signal detected by the detector; determine whether a medical condition is indicated based on at least the concentration of the clinically-relevant analyte; and, in response to a determination that the medical condition is indicated, transmit data representative of the medical condition via the communication interface. The device may also include a signal source configured to transmit an interrogating signal into the portion of subsurface vasculature, thereby generating a response signal in response to the interrogating signal.

Test Platform for Wrist-Mounted Physiologic Measurement Device

Inventors: Andrew Conrad, Eric Peeters

Filed Jun 21, 2013

Published Dec 25, 2014

Abstract:

A test model has an outer polymer layer that models an exterior surface of a human arm and includes at least a wrist portion, an inner polymer core that is at least partially surrounded by the outer polymer layer and extends into the wrist portion, and polymer tubing adjacent to the inner polymer core. The polymer tubing is at least partially surrounded by the outer polymer layer and extends into the wrist portion. The polymer tubing has a first fluid inlet and a first fluid outlet. The test model is substantially free of metallic and magnetic materials.

Physiological Measurement Using Wearable Device

Inventors: Andrew Conrad, Eric Peeters

Filed Jun 21, 2013

Published 20140378777

Dec 25, 2014

Abstract:

A method for real-time, high-density physiological data collection includes automatically measuring, by a wearable device, one or more physiological parameters during each of a plurality of measurement periods, and upon conclusion of a measurement period, for each of the plurality of measurement periods, automatically transmitting by the wearable device data representative of the physiological parameters measured during that measurement period, to a server, the server configured to develop a baseline profile based on the data transmitted by the wearable device for the plurality of measurement periods. The measurement periods may extend through a plurality of consecutive days, and each of the consecutive days may include multiple measurement periods. At least some of the physiological parameters are measured by non-invasively detecting one or more analytes in blood circulating in subsurface vasculature proximate to the wearable device.

Container

Inventors: Jeffrey George Linhardt, Daniel Barrows

Filed Jun 24, 2013

Granted Jun 2, 2015

Abstract:

The present disclosure provides an apparatus including a first chamber containing an eye-mountable device. The apparatus may also include a second chamber containing an aqueous solution. The apparatus may also include a membrane positioned between the first chamber and the second chamber. The membrane may be configured to rupture based on application of a force to the apparatus. The ruptured membrane may allow the aqueous solution to engage with the eye-mountable device. The apparatus may also include a lid to seal one or more of the first chamber and the second chamber.

Device Identification

Inventors: Daniel Yeager, Brian Otis, Andrew Nelson

Filed Jun 28, 2013

Published Jan 1, 2015

Abstract:

An eye-mountable device includes a controller embedded in a polymeric material configured for mounting to a surface of an eye. The controller is electrically connected to an antenna included in the eye-mountable device. The controller is configured to: (i) receive an indication of an interrogation signal via the antenna, (ii) responsive to the interrogation signal, output a substantially unique identification sequence; and (iii) use the antenna to communicate the substantially unique identification sequence. The substantially unique identification sequence can then be used by external readers to associate the eye-mountable device with device-specific information without storing such information on the eye-mountable device.

Methods for Adhering a Substrate to a Polymer Layer

Inventors: Zenghe Liu, Jeffrey George Linhardt

Filed Jun 28, 2013

Published Jan 1, 2015

Abstract:

The present disclosure provides a method including forming a polymer layer defining a side of an eye-mountable device. The method may also include providing an adhesive in a ring-shaped pattern on a ring-shaped substrate or on the first polymer layer. The method may also include providing the ring-shaped substrate on the first polymer layer in a predetermined rotational orientation. The method may also include applying a force to one or more of the ring-shaped substrate and the polymer layer to adhere the first polymer layer to the ring-shaped substrate. The method may also include curing the ring-shaped substrate and the first polymer layer.

Chemically Reactive Enzyme Immobilization

Inventors: Zenghe Liu, Jeffrey George Linhardt

Filed Jun 28, 2013

Published Jan 1, 2015

Abstract:

An analyte sensor for the continuous or semi-continuous monitoring of physiological parameters and a method for making the analyte sensor are disclosed. The analyte sensor includes a crosslinked, hydrophilic copolymer sensing layer in contact with a surface of an electrode, where the sensing layer includes methacrylate-derived backbone chains having covalent bonds to an analyte sensing component. The method includes combining the precursor components of the sensing layer, depositing the combined mixture on a surface of an electrode, and curing the deposited mixture.

Porous Polymeric Formulation Prepared Using Monomer

Inventors: Zenghe Liu, Jeffrey George Linhardt

Filed Jun 28, 2013

Published Jan 1, 2015

Abstract:

An analyte sensor for the continuous or semi-continuous monitoring of physiological parameters and a method for making the analyte sensor are disclosed. In one aspect, the analyte sensor includes a crosslinked, hydrophilic copolymer in contact with a surface of an electrode, and an analyte sensing component embedded within the crosslinked, hydrophilic copolymer. The crosslinked, hydrophilic copolymer has methacrylate-derived backbone chains of first methacrylate-derived units, second methacrylate-derived units and third methacrylate-derived units. The first and second methacrylate-derived units have side chains that can be the same or different, and the third methacrylate-derived units in different backbone chains are connected by hydrophilic crosslinks.

Porous Polymeric Formulation Prepared Using Porogens

Inventors: Jeffrey George Linhardt, Zenghe Liu, Huanfen Yao

Filed Jun 28, 2013

Published Jan 1, 2015

Abstract:

An analyte sensor for the continuous or semi-continuous monitoring of physiological parameters and a method for making the analyte sensor are disclosed. The analyte sensor includes a crosslinked copolymer network in contact with a surface of an electrode. The copolymer network has voids formed by the removal of a porogen, and an analyte sensing component is immobilized within the network. The method involves forming a solution of the precursors of the copolymer, depositing the mixture on a surface of an electrode, and curing the deposited mixture to provide the analyte sensor.

Enzyme Immobilization by Crosslinking

Inventors: Zenghe Liu

Filed Jun 28, 2013

Published Jan 1, 2015

Abstract:

An analyte sensor for the continuous or semi-continuous monitoring of physiological parameters and a method for making the analyte sensor are disclosed. In one aspect, the analyte sensor includes an electrode, a sensing layer in contact with a surface of the electrode, and a protective membrane. The sensing layer is a crosslinked, hydrophilic copolymer including poly(alkylene oxide) and poly(vinyl pyridine), and an analyte sensing component is immobilized within the crosslinked, hydrophilic copolymer. The protective membrane is a crosslinked, hydrophilic copolymer including alkylene oxide, vinyl pyridine and styrene units. The method involves the formation of a sensing layer on a surface of an electrode, followed by the formation of a protective membrane on a surface of the sensing layer.

Methods for Forming a Channel Through a Polymer Layer Using One or More Photoresist Layers

Inventors: Huanfen Yao, Babak Parviz, Jeffrey George Linhardt

Filed Jun 28, 2013

Granted May 12, 2015

Abstract:

A method may involve forming one or more photoresist layers over a sensor located on a structure, such that the sensor is covered by the one or more photoresist layers. The sensor is configured to detect an analyte. The method may involve forming a first polymer layer. Further, the method may involve positioning the structure on the first polymer layer. Still further, the method may involve forming a second polymer layer over the first polymer layer and the structure, such that the structure is fully enclosed by the first polymer layer, the second polymer layer, and the one or more photoresist layers. The method may also involve removing the one or more photoresist layers to form a channel through the second polymer layer, wherein the sensor is configured to receive the analyte via the channel.

Devices and Methods for a Contact lens with an Outward Facing Light Source

Inventors: Brian Otis, Robert Francis Wiser, Andrew Nelson

Filed Jun 28, 2013

Granted Sep 16, 2014

Abstract:

A body-mountable device can include a transparent material and a substrate at least partially embedded in the transparent material. The transparent material can have a mounting surface and a surface opposite the mounting surface. A light source can be disposed on the substrate and configured to emit light through the surface opposite the mounting surface. The light source can be controlled by circuitry disposed on the substrate. The circuitry can be configured to receive modulation instructions and modulate the light emitted by the light source based on the modulation instructions.

Devices and Methods for a Contact lens with an Inward Facing Light SourceE

Inventors: Brian Otis, William James Biederman

Filed Jun 28, 2013

Published Jan 1, 2015

Abstract:

An eye-mountable device can include a transparent material and a substrate at least partially embedded in the transparent material. The transparent material can have a concave surface and a convex surface, with the concave surface configured to removably mount the eye-mountable device on a corneal surface overlaying a pupil. A light source can be disposed on the substrate and configured to emit light through the concave surface and towards the corneal surface such that the emitted light is viewable through the pupil. The light source can be controlled by circuitry disposed on the substrate. The circuitry can be configured to modulate the light emitted by the light source to provide modulated light.

Reader Communication with Contact Lens Sensors and Display Device

Inventors: Frank Honor, Andrew Nelson, Brian Otis

Filed Jun 28, 2013

Granted Dec 30, 2014

Abstract:

A reader for communicating with both an eye-mountable device and a display device is provided. The reader can transmit radio frequency power to a tag that is part of the eye-mountable device. The reader can communicates with the tag using a first protocol. Communicating with the tag can include having the reader request data from the tag and receive the requested data from the tag. The reader can process the received data. The reader can store the processed data. The reader can communicates with the display device using a second protocol, where the first and second protocols can differ. Communicating with the display device can include having the reader transmit the stored data to the display device. The display device can receive the transmitted data, process the transmitted data, and generate one or more displays including the transmitted and/or processed data.

Using Unique Identifiers to Retrieve Configuration Data for Tag Devices

Inventors: Alice Lin, Andrew Nelson, Daniel Yeager, Brian Otis

Filed Aug 22, 2013

Granted Feb 2, 2016

Abstract:

Methods and systems for using unique identifiers to retrieve configuration data for tag devices are described herein. An example method may involve obtaining a unique identifier associated with a tag device. The tag device may include an antenna and a sensor configured to obtain sensor readings that can be wirelessly transmitted to a reader device via the antenna. The method may also involve determining configuration parameters associated with the tag device based on the unique identifier. The method may further involve storing, in at least one memory, at least a portion of the configuration parameters in association with the unique identifier.

Sacrificial Layers for Bio-Compatible Devices

Inventors: James Etzkorn, Harvey Ho, Huanfen Yao

Filed Aug 27, 2013

Published Mar 5, 2015

Abstract:

A method may involve: forming a sacrificial layer on a working substrate; forming a first bio-compatible layer on the sacrificial layer such that the first bio-compatible layer adheres to the sacrificial layer; forming a conductive pattern on the first bio-compatible layer; mounting an electronic component to the conductive pattern; forming a second bio-compatible layer over the first bio-compatible layer, the electronic component, and the conductive pattern; and removing the sacrificial layer to release the bio-compatible device from the working substrate. The first bio-compatible layer defines a first side of a bio-compatible device. The second bio-compatible layer defines a second side of the bio-compatible device.

Nanoparticle Phoresis

Inventors: Andrew Jason Conrad

Filed Sep 5, 2013

Published Mar 5, 2015

Abstract:

Functionalized particles in the blood are able to selectively bind to targets in the blood that have adverse health effects. The binding of the particles to the targets allows the targets to be selectively modified or destroyed by energy from outside the body such that the adverse health effects are reduced or eliminated. The energy is generated by a wearable device which is able to direct the energy into the subsurface vasculature of the wearer of the wearable device. Further, one or more of the functionalized particles may be magnetic, allowing a magnetic field generated by the wearable device and directed into the subsurface vasculature to concentrate the bound targets in a lumen of the subsurface vasculature proximate to the wearable device.

Delivery of Functionalized Particles

Inventors: Andrew Jason Conrad

Filed Sep 5, 2013

Published Mar 5, 2015

Abstract:

A device includes a capsule sized to pass through a lumen of a gastrointestinal tract, a plurality of functionalized particles disposed within the capsule, one or more tissue penetrating members configured to puncture a wall of the lumen of the intestinal tract; and an actuator having a first configuration and a second configuration. The actuator is configured to retain the plurality of functionalized particles within the capsule in the first configuration. The actuator is further configured to advance the plurality of functionalized particles from the capsule into a wall of the lumen of the gastrointestinal tract via the one or more tissue penetrating members by the actuator transitioning from the first configuration to the second configuration. Systems including the device and methods of delivering functionalized particles to the body are also provided.

Assembling Thin Silicon Chips on a Contact Lens

Inventors: James Etzkorn

Filed Sep 12, 2013

Granted Jun 9, 2015

Abstract:

A contact lens having a thin silicon chip integrated therein is provided along with methods for assembling the silicon chip within the contact lens. In an aspect, a method includes creating a plurality of lens contact pads on a lens substrate and creating a plurality of chip contact pads on a chip. The method further involves applying assembly bonding material to the each of the plurality of lens contact pads or chip contact pads, aligning the plurality of lens contact pads with the plurality of chip contact pads, bonding the chip to the lens substrate via the assembly bonding material using flip chip bonding, and forming a contact lens with the lens substrate.

Devices and Methods for a Contact lens with an Outward Facing Light Source

Inventors: Brian Otis, Robert Francis Wiser, Andrew Nelson

Filed Sep 16, 2013

Granted Sep 9, 2014

Abstract:

A body-mountable device can include a transparent material and a substrate at least partially embedded in the transparent material. The transparent material can have a mounting surface and a surface opposite the mounting surface. A light source can be disposed on the substrate and configured to emit light through the surface opposite the mounting surface. The light source can be controlled by circuitry disposed on the substrate. The circuitry can be configured to receive modulation instructions and modulate the light emitted by the light source based on the modulation instructions.

Devices and Methods for a Contact lens with an Inward Facing Light Source

Inventors: Brian Otis, William James Biederman

Filed Sep 16, 2013

Granted Jul 1, 2014

Abstract:

An eye-mountable device can include a transparent material and a substrate at least partially embedded in the transparent material. The transparent material can have a concave surface and a convex surface, with the concave surface configured to removably mount the eye-mountable device on a corneal surface overlaying a pupil. A light source can be disposed on the substrate and configured to emit light through the concave surface and towards the corneal surface such that the emitted light is viewable through the pupil. The light source can be controlled by circuitry disposed on the substrate. The circuitry can be configured to modulate the light emitted by the light source to provide modulated light.

Reader Communication With Contact Lens Sensors and Display Device

Inventors: Brian Otis, Frank Honor, Andrew Nelson

Filed Sep 16, 2013

Granted Sep 8, 2015

Abstract:

A reader for communicating with both an eye-mountable device and a display device is provided. The reader can transmit radio frequency power to a tag that is part of the eye-mountable device. The reader can communicates with the tag using a first protocol. Communicating with the tag can include having the reader request data from the tag and receive the requested data from the tag. The reader can process the received data. The reader can store the processed data. The reader can communicates with the display device using a second protocol, where the first and second protocols can differ. Communicating with the display device can include having the reader transmit the stored data to the display device. The display device can receive the transmitted data, process the transmitted data, and generate one or more displays including the transmitted and/or processed data.

Device With Dual Power Sources

Inventors: Nathan Pletcher, Daniel Yeager, William James Biederman, Andrew Nelson

Filed Sep 16, 2013

Granted Jun 3, 2014

Abstract:

A wearable device includes a sensor, auxiliary electronics, a primary power supply configured to harvest radio frequency (RF) radiation received from an external reader and use the harvested RF radiation to power the sensor, and an auxiliary power supply configured to harvest energy other than that received from the external reader and use the harvested energy to supply power to the sensor and/or the auxiliary electronics. The external reader may supply less power in response to operation of the auxiliary power supply. Additionally or alternatively, in response to a determination that the auxiliary power supply is unable to supply power, the wearable device may disable all auxiliary electronics but for the sensor. In response to a determination that the primary power supply is unable to supply power but the auxiliary power supply is able to supply power, the wearable device may retain operating parameters in the memory storage unit using the auxiliary power supply.

Contact Lenses Having Two-Electrode Electrochemical Sensors

Inventors: Zenghe Liu

Filed Sep 17, 2013

Published Jul 10, 2014

Abstract:

Apparatus, systems and methods employing contact lenses with two-electrode electrochemical sensors are provided. In some aspects, the contact lens includes: a substrate that forms at least part of a body of the contact lens; and a circuit, disposed on or within the substrate, and including a two-electrode electrochemical sensor. The two-electrode electrochemical sensor can include: a working electrode; and a combination reference-counter electrode. The electrochemical sensor can be an amperometric sensor that senses a biological feature of a wearer of the contact lens. The working electrode can generate a signal indicative of the sensed analyte, and the combination reference-counter electrode can pass the signal generated from the working electrode. The signal can be employed to determine the analyte concentration of a solution in contact with the contact lens.

Contact Lens with Integrated Pulse Oximeter

Inventors: Harvey Ho, Babak Amirparviz

Filed Sep 17, 2013

Granted Dec 9, 2014

Abstract:

Apparatus, systems and methods employing a contact lens having a pulse oximetry sensor to detect information indicative of a blood oxygen content and/or pulse rate of a wearer of the contact lens, are provided. In some aspects, a contact lens includes a substrate that forms at least part of a body of the contact lens and a pulse oximetry sensor located on or within the substrate that detects information associated with at least one of blood oxygen content or a pulse rate of a wearer of the contact lens. The pulse oximetry sensor comprises one or more light emitting diodes that illuminate a blood vessel of at least one of a region of an eye or an eyelid and a detector that receives light reflected from the blood vessel and generates the information.

In-vitro Calibration Of An Ophthalmic Analyte Sensor

Inventors: Brian Otis, Zenghe Liu

Filed Sep 19, 2013

Published Apr 17, 2014

Abstract:

An eye-mountable device includes an electrochemical sensor embedded in a polymeric material configured for mounting to a surface of an eye. The electrochemical sensor includes a working electrode, a reference electrode, and a reagent that selectively reacts with an analyte to generate a sensor measurement related to a concentration of the analyte in a fluid to which the eye-mountable device is exposed. A calibration-solution measurement is obtained while the eye-mountable device is exposed to a calibration solution. A calibration value is determined based on at least the calibration-solution measurement and an analyte concentration of the calibration solution. A tear-film measurement is obtained while the eye-mountable device is mounted to an eye so as to be exposed to tear film. The analyte concentration of the tear film is determined based on at least the tear-film measurement and the calibration value.

Encapulated Electronics

Inventors: James Etzkorn, Babak Amirparviz

Filed Sep 19, 2013

Granted Nov 11, 2014

Abstract:

An eye-mountable device includes an electrochemical sensor embedded in a polymeric material configured for mounting to a surface of an eye. The electrochemical sensor includes a working electrode and a reference electrode that reacts with an analyte to generate a sensor measurement related to a concentration of the analyte in a fluid to which the eye-mountable device is exposed. An example assembly process includes: forming a sacrificial layer on a working substrate; forming a first layer of a bio-compatible material on the sacrificial layer; providing an electronics module on the first layer of the bio-compatible material, forming a second layer of the bio-compatible material to cover the electronics module; and annealing the first and second layers of the bio-compatible material together to form an encapsulated structure having the electronics module fully encapsulated by the bio-compatible material.

Standby Biasing Of Electrochemical Sensor To Reduce Sensor Stabilization Time During Measurement

Inventors: Nathan Pletcher, Brian Otis

Filed Sep 20, 2013

Granted Jan 6, 2015

Abstract:

An eye-mountable device includes an electrochemical sensor embedded in a polymeric material configured for mounting to a surface of an eye. The electrochemical sensor applies a stabilization voltage between a working electrode and a reference electrode to allow the amperometric current to stabilize before powering measurement electronics configured to measure the amperometric current and communicate the measured amperometric current. The electrochemical sensor consumes less power while applying the stabilization voltage than during the measurement. The measurement is initiated in response to receiving a measurement signal at an antenna in the eye-mountable device.

Systems and Methods for Encapsulating Electronics in a Mountable Device

Inventors: James Etzkorn

Filed Sep 20, 2013

Granted Feb 10, 2015

Abstract:

A mountable device includes a bio-compatible structure embedded in a polymer that defines at least one mounting surface. The bio-compatible structure includes an electronic component having electrical contacts, sensor electrodes, and electrical interconnects between the sensor electrodes and the electrical contacts. The bio-compatible structure is fabricated such that it is fully encapsulated by a bio-compatible material, except for the sensor electrodes. In the fabrication, the electronic component is positioned on a first layer of bio-compatible material and a second layer of bio-compatible material is formed over the first layer of bio-compatible material and the electronic component. The electrical contacts are exposed by removing a portion of the second layer, a conductive pattern is formed to define the sensor electrodes and electrical interconnects, and a third layer of bio-compatible material is formed over the conductive pattern. The sensor electrodes are exposed by removing a portion of the third layer.

Systems and Methods for Encapsulating Electronics in a Mountable Device

Inventors: James Etzkorn

Filed Sep 23, 2013

Granted Apr 21, 2015

Abstract:

A mountable device includes a bio-compatible structure embedded in a polymer that defines at least one mounting surface. The bio-compatible structure includes an electronic component having electrical contacts, sensor electrodes, and electrical interconnects between the sensor electrodes and the electrical contacts. The bio-compatible structure is fabricated such that it is fully encapsulated by a bio-compatible material, except for the sensor electrodes. In the fabrication, the electronic component is positioned on a first layer of bio-compatible material and a second layer of bio-compatible material is formed over the first layer of bio-compatible material and the electronic component. The electrical contacts are exposed by removing a portion of the second layer, a conductive pattern is formed to define the sensor electrodes and electrical interconnects, and a third layer of bio-compatible material is formed over the conductive pattern. The sensor electrodes are exposed by removing a portion of the third layer.

Device Having Embedded Antenna

Inventors: James Etzkorn, Stephen ODriscoll

Filed Sep 24, 2013

Published Dec 18, 2014

Abstract:

Body-mountable devices and methods for embedding a structure in a body-mountable device are described. A body-mountable device includes a transparent polymer and a structure embedded in the transparent polymer. The transparent polymer defines a posterior side and an anterior side of the body-mountable device. The structure has an outer diameter and an inner diameter and includes a sensor configured to detect an analyte and an antenna. The antenna includes a plurality of conductive loops spaced apart from each other between the outer diameter and the inner diameter.

Information Processing Method

Inventors: Ehsan Saeedi, Babak Amirparviz

Filed Sep 24, 2013

Published Mar 27, 2014

Abstract:

Systems, apparatus and methods including a contact lens that facilitates collection and/or processing of information associated with sensed features are provided. In one aspect, a system can include a contact lens and an analysis component external to the contact lens. The contact lens can include: a substrate; and a circuit, disposed on or within the substrate. The circuit can include: a plurality of sensors configured to sense respective features associated with a wearer of the contact lens; and a communication component configured to communicate information indicative of sensed features. The analysis component can be configured to: receive the information indicative of the sensed features; and generate statistical information based, at least, on the information indicative of the sensed features.

Container

Inventors: Jeffrey George Linhardt, Daniel Barrows

Filed Sep 24, 2013

Granted Nov 11, 2014

Abstract:

The present disclosure provides an apparatus including a first chamber containing an eye-mountable device. The apparatus may also include a second chamber containing an aqueous solution. The apparatus may also include a membrane positioned between the first chamber and the second chamber. The membrane may be configured to rupture based on application of a force to the apparatus. The ruptured membrane may allow the aqueous solution to engage with the eye-mountable device. The apparatus may also include a lid to seal one or more of the first chamber and the second chamber.

Method And System For Measuring Pyruvate

Inventors: Huanfen Yao, Zenghe Liu

Filed Oct 17, 2013

Granted Aug 4, 2015

Abstract:

A body-mountable pyruvate sensing device includes an electrochemical sensor embedded in a polymeric material configured for mounting to a surface of an eye. The electrochemical sensor includes a working electrode, a reference electrode, and a reagent localized near the working electrode that selectively reacts with pyruvate. Application of a voltage between the working electrode and the reference electrode causes a current related to a concentration of pyruvate in a fluid to which the electrochemical sensor is exposed; the current is measured by the body-mountable device and wirelessly communicated.

Method And System For Measuring Urea

Inventors: Huanfen Yao, Zenghe Liu

Filed Oct 17, 2013

Published Apr 23, 2015

Abstract:

A body-mountable urea sensing device includes an electrochemical sensor embedded in a polymeric material configured for mounting to a surface of an eye. The electrochemical sensor includes a working electrode, a reference electrode, and a reagent localized near the working electrode that selectively reacts with urea. A potentiometric voltage between the working electrode and the reference electrode is related to a concentration of urea in a fluid to which the electrochemical sensor is exposed; the voltage is measured by the body-mountable device and wirelessly communicated.

Modulation of a Response Signal to Distinguish Between Analyte and Background Signals

Inventors: Jason Thompson, Andrew Conrad, Eric Peeters, Vikram Singh Bajaj, Mark Askew

Filed Oct 23, 2013

Published Apr 23, 2015

Abstract:

A method for modulating a response signal includes introducing functionalized particles into a lumen of subsurface vasculature, wherein the functionalized particles are configured to interact with one or more target analytes present in blood circulating in the subsurface vasculature; and non-invasively detecting the one or more target analytes. A response signal, which may include a background signal and an analyte response signal related to interaction of the functionalized particles with the one or more target analytes, is transmitted from the subsurface vasculature. A modulation configured to alter the response signal such that the analyte response signal is affected differently than the background signal may be applied to a portion of subsurface vasculature. Analyte detection may be achieved by differentiating the analyte response signal from the background.
21 Avr 2016
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